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Thanquol is an ambitious, ruthless, and cunning Grey Seer of the Skaven. First appearing in the Gotrek & Felix (novel series) in which he becomes the titular duo's long-standing nemesis, he later appears in his own series of novels, the Thanquol & Boneripper (novel series), which chronicle his adventures between his last appearance in Beastslayer and his reappearance in Elfslayer.
Thanquol first appears in Skavenslayer as the skaven chosen by the Council of Thirteen to lead the army preparing to attack Nuln after the previous leader was slain by Gotrek. Taking command of the skaven forces from various clans, Thanquol's early leadership was spent uncovering and foiling the plans of the other leaders within his army, which he saw as threats to his position. Paranoid and egotistical to the point of megalomania, Thanquol like all skaven leaders consistently blames his failures on the incompetence of his underlings and the machinations of hidden enemies within skaven society. He is addicted to Warpstone snuff, which fuels his formidable sorcerous powers but also damages his mental condition.
Though a powerful sorcerer with great malicious intent, Thanquol's tendency to leave his plans in the paws of less capable underlings and consistently underestimate his foes often ends up foiling his schemes. The invasion of Nuln which he oversaw ultimately ended in failure due to a number of factors including the mutation of a Clan Pestilens plague to affect skaven as well as humans, the unstoppable spread of rats specifically bred to devour all available foodstuffs and the interference of Gotrek and Felix. Despite managing to penetrate the palace with a company of stormvermin, Thanquol was prevented from murdering Countess Emmanuelle by Gotrek and Felix's intervention. After his defeat he fled, as always justifying his cowardice as prudent skaven caution.
Very soon after first encountering them Thanquol began to regard Gotrek and Felix and his arch-enemies, near-demonic agents of a malign power sent to foil his otherwise perfect plans. His many attempts to have them killed have all ended in failure. Despite the threat he poses the duo were for a long time far less aware of him than he was of them, knowing him only as a shadowy figure controlling the skaven. As such Thanquol was surprised and infuriated when upon finally capturing the pair and acting as if their long rivalry was about to end neither Gotrek nor Felix recognized him. Nevertheless Thanquol's murder of Felix's father, Gustav Jaeger, has finally made him the hated nemesis to them that he always believed he was.
After his failure to conquer Nuln Thanquol's investigation into reports that a colony of skaven had been driven from their tunnels beneath an abandoned mine led to his discovery of the Lonely Tower. Desiring the claim the secrets of Dwarfen engineering compiled there for himself Thanquol launched an attack on the engineering camp despite the shocking arrival of Gotrek and Felix at the same remote place. His forces were defeated in the Battle of the Lonely Tower, but upon learning of the airship Spirit of Grungni from his underling Lurk Snitchtongue capturing it became Thanquol's new goal. Using his mental link with Lurk to follow the airship to Kislev, he later led a force of Clan Moulder soldiers to capture the Straghov Manse, from where he planned to ambush the airship upon its return from the Chaos Wastes. He came dangerously close to succeeding, being foiled only by the escape of the prisoners from the manse and Max Schreiber's countering of the spell he used to immobilize the airship. Escaping his defeat with only a mutated Lurk for protection, Thanquol fled across the grass-plains of Kislev before being captured by outriders of the vast Chaos army led by Arek Daemonclaw. Released by the Chaos warlord only to be captured by Clan Moulder and taken to Hell Pit to account for the loss of their troops, Thanquol earned his freedom by helping crush Lurk's rebellion against the Moulder overseers. Placed in command of a Clan Moulder force sent to investigate the great gathering of dark energy near Praag, Thanquol's army came under attack by Khornate Chaos Warriors from Daemonclaw's host. The outcome of that battle is unknown, though Daemonclaw's overall host was destroyed.
After his adventures in the Thanquol & Boneripper series, Thanquol lost enough status to be banished by the Council of Thirteen to an outpost in the backwaters of Estalia, where he discovered his two greatest nemeses were still alive, 20 years after his last encounter with them. In the novel Elfslayer, he manages to capture the pair and plans to torture them to death in recompense for all they have done to him, but after a High Elf prisoner mentions they were trying to recover a Dark Elf weapon known as the 'Harp of Ruin', Thanquol released them and allowed the Druchii to capture them, hoping they will cause enough destruction for him to steal it. The plan worked at first, in that Thanquol's agents were able to steal the harp, but failed in that Gotrek destroyed the Harp, killed most of the Dark Elves and Skaven trying to recover it, and came incredibly close to killing Thanquol himself: though the Grey Seer survived, he lost his right hand to Gotrek's axe, and has vowed to take revenge for the injury. Likewise, Felix and Gotrek have vowed to kill him the next time they meet, on account of the fact Thanquol's minions tortured Felix's father, Gustav, to death while trying to gain information on the pair's whereabouts.
As well as his adventures in the novel series Thanquol is also known to have attempted to use ancient Elf stones to destroy the lands of men, a scheme which was thwarted by Commander Morgan Bernhardt and his army. He also once tried to summon a Verminlord of the Horned Rat to aid an underground assault on Karak Kadrin, but this plan failed spectacularly when he instead managed to summon Skarbrand, a Bloodthirster of Khorne, who swiftly annihilated the Skaven army before fading away. As is expected, the only survivor of this slaughter was Thanquol, who fled to safety at the first sign of trouble.
Thanquol often employs mutated Rat Ogre bodyguards for protection, each called Boneripper. The first was slain by Gotrek in the manse of Fritz von Halstadt in Nuln, the second by Felix , who threw a bomb down its throat in the Battle of the Lonely Tower. Recently, Clan Skryre gave Thanquol an important gift as a sign of reconciliation for past deeds. Clan Eshin warriors were hired to recover the body of Thanquol's first Rat Ogre, which had been on display in a freak show in Nuln. Clan Skyre reassembled the cadaver and reanimated it as a mindless machine at the order of Thanquol.